base

base

Base class for DSC deconvolution methods.

Deconvolution recovers the tissue residue function R(t) from the observed concentration-time curve C(t) and the arterial input function (AIF):

C(t) = CBF * AIF(t) ** R(t)

where ** denotes convolution. The residue function describes the fraction of tracer still present in the tissue at time t after an ideal bolus injection.

References

.. [1] OSIPI CAPLEX, https://osipi.github.io/OSIPI_CAPLEX/ .. [2] Dickie BR et al. MRM 2024. doi:10.1002/mrm.30101

BaseDeconvolver

Bases: BaseComponent

Abstract base class for deconvolution methods.

Subclasses implement specific deconvolution algorithms (sSVD, cSVD, oSVD) to recover the residue function and estimate perfusion parameters including CBF (OSIPI: Q.PH1.003), MTT (OSIPI: Q.PH1.006), and arterial delay Ta (OSIPI: Q.PH1.007).

References

.. [1] OSIPI CAPLEX, https://osipi.github.io/OSIPI_CAPLEX/

deconvolve abstractmethod

deconvolve(concentration, aif, time, mask=None, **kwargs)

Perform deconvolution to recover the residue function.

PARAMETER	DESCRIPTION
concentration	Tissue concentration curves. TYPE: NDArray[floating]
aif	Arterial input function. TYPE: NDArray[floating]
time	Time points in seconds. TYPE: NDArray[floating]
mask	Brain mask. TYPE: NDArray[bool_] | None DEFAULT: None
**kwargs	Method-specific parameters. TYPE: Any DEFAULT: {}

RETURNS	DESCRIPTION
DeconvolutionResult	Residue function and derived perfusion parameters.