Task Forces¶
OSIPI's aims are addressed through dedicated Task Forces. The objectives, time plan, leadership, and members of each task force for the years 2026-2028 are defined in the Roadmap. More details and contacts are available below.
To achieve OSIPI's mission, six specific aims were identified. Each aim is supported by one to three task forces (TF), generally split by non-contrast (arterial spin labeling; ASL) and contrast-agent-based (dynamic susceptibility contrast; DSC; and dynamic contrast enhanced; DCE) perfusion MRI. From the second roadmap, intravoxel incoherent motion (IVIM) was also added.
Aim 1 — Software Inventories¶
Inventories and evaluation of available complete perfusion image analysis tools for end-users.
TF1.1 — ASL software inventory
Inventory of publicly available ASL pipelines along with their features, compatibility, and links to manuals and source code.
TF1.2 — DCE/DSC inventory (inactive)
Inventory of software packages for DCE/DSC image analysis. This task force is currently inactive due to insufficient members.
Aim 2 — Code Libraries¶
Develops community-driven open-source code libraries for perfusion imaging analysis.
TF2.2 — ASL code contributions
Code collection of open-source functions, scripts, and in-house pipelines for ASL perfusion imaging analysis.
TF2.3 — DSC/DCE code contributions
Tested code collection of open-source Python functions for DCE/DSC perfusion imaging analysis.
TF2.4 — IVIM code contributions
Gathered and tested code for intravoxel incoherent motion (IVIM) analysis, with model fitting code in Python and Matlab.
TF2.5 — Open-source ASL
Demonstrate feasibility of acquiring ASL data across multiple vendors using 100% open-source tools
TF2.6 — OSIPI python package
To develop OSIPY, a community-led open source python library for quantitative perfusion MRI that replaces fragmented, in-house analysis tools with a standardized, reproducible, and accessible solution
TF2.7 — IVIM preprocessing
The taskforce aims to develop a code repository that implements all necessary preprocessing steps for IVIM data.
Aim 3 — Data Inventory¶
Inventories with open-access (pre-)clinical or phantom data and digital reference objects (DROs).
TF3.1 — Digital Reference Objects and Phantoms
Inventory of digital reference objects and phantom data for perfusion MRI.
TF3.2 — Clinical and preclinical data (inactive)
Inventory of freely available clinical and preclinical perfusion MRI data. This task force is currently inactive due to insufficient members.
TF3.3— IVIM big data collection
To establish the extent to which site-, and vendor-specific differences impact quantitative IVIM measurement outcomes.To create a controlled-access repository of in vivo multi-site IVIM test-retest data
TF3.4 — Data Register
The taskforce aims to set-up a data registry of perfusion MRI to enable easier collaboration across the community
Aim 4 — Lexicons¶
Develop terminology and reporting guidelines for image acquisition and perfusion image analysis.
TF4.1 — ASL Lexicon
Standardized terminology and reporting recommendations for arterial spin labeling imaging.
TF4.2 — DSC/DCE Lexicon (CAPLEX)
Lexicon of definitions for quantities, models, and analysis methods used in contrast-agent-based perfusion MRI.
TF4.4 — BBB MRI lexicon
To define standardized terminology, mathematical models, and best practices for BBB-MRI and to evaluate differences between BBB MRI approaches via simulations or experimental studies
TF4.5 — IVIM lexicon
To harmonize terminology for intravoxel incoherent motion (IVIM) though the development of a community-endorsed lexicon
TF4.6 — Method section generator
To develop publicly available online tool that would serve beginner-intermediate users of MRI perfusion techniques to correctly report the acquisition settings
Aim 5 — Exchange and Education platform¶
Dissemination of resources through website and educational activities.
TF5.1 — Website
Develops and maintains the OSIPI website for sharing resources with the community.
TF5.2 — Education
Develops educational activities and materials for perfusion imaging.
TF5.3 — AURA artifact repository
To create an artifact inventory for perfusion imaging, including ASL, DCE and DSC
TF5.4 — Clinical case reports
To compile a collection of clinical ASL case reports featuring commonly encountered pathologies and characteristic image findings
Aim 6 — Challenges¶
Develop challenges that compare the performance of perfusion image analysis software.
TF6.1 — ASL challenges
Develops challenges comparing ASL perfusion image analysis software.
TF6.2 — DSC/DCE challenges
Develops challenges comparing DSC/DCE perfusion image analysis software.
TF6.3 — IVIM algorithm comparison
To study, quantify and explain the differences between IVIM fitting algorithms using the OSIPI IVIM code collection